文献类型：期刊文献

英文题名：Taking Advantage of a Sustainable Forest Resource in Agriculture: A Value-Added Application of Volatile Turpentine Analogues as Botanical Pesticides Based on Amphipathic Modification and QSAR Study

作者：Li, Jian[1] Li, Jingjing[1] Gao, Yanqing[2] Shang, Shibin[3] Song, Zhanqiang[3] Xiao, Guomin[4]

第一作者：Li, Jian

通信作者：Gao, YQ[1];Xiao, GM[2]

机构：[1]Northwest A&F Univ, Coll Forestry, 3 Taicheng Rd, Yangling 712100, Shaanxi, Peoples R China;[2]Northwest A&F Univ, Coll Plant Protect, 23 Xinong Rd, Yangling 712100, Shaanxi, Peoples R China;[3]Chinese Acad Forestry, Inst Chem Ind Forest Prod, Longpan Rd, Nanjing 210042, Jiangsu, Peoples R China;[4]Southeast Univ, Sch Chem & Chem Engn, 2 Dongnan Daxue Rd, Nanjing 211189, Jiangsu, Peoples R China

年份：2016

卷号：4

期号：9

起止页码：4685-4691

外文期刊名：ACS SUSTAINABLE CHEMISTRY & ENGINEERING

收录：;EI(收录号：20163702791909);Scopus(收录号：2-s2.0-84985961093);WOS:【SCI-EXPANDED(收录号:WOS:000382713100024)】；

基金：The National Nature Science Foundation of China (Project No. 31401783 and Project No. 31400509), Chinese Universities Scientific Fund (Project No. Z109021513), and Open Foundation of Key Laboratory of Biomass Energy and Materials of Jiangsu Province (Project No. JSBEM201608) provided financial support for this research.

语种：英文

外文关键词：Turpentine; beta-Pinene; Insecticidal activity; QSAR

摘要：As a continuous study on the integrated application of volatile beta-pinene as an abundant bioresource, the further and broader activity assessment of beta-pinene analogues was necessary. On the basis of previous research, the larvicidal activities were carried out against two agricultural insect pests Plutella xylostella and Mythimna separata. In accordance with the overall insecticidal effect, it was remarkable that compounds 5k and 5l demonstrated extreme activity, with LC50 values 1.846 and 1.621 mu g/mL against Plutella xylostella. The preliminary structure activity relationship (SAR) was analyzed, and compounds with the appropriate amphipathic feature displayed more desirable performance. In the meantime, the quantitative structure-activity relationship (QSAR) model (R-2 = 0.9485, F = 82.94, S-2 = 0.0067) was built. The model indicated the most important structural feature was the Id, value, which represented the total hybridization components of the molecular dipole. The work provided a potential and alternative approach to take advantage of a forest resource in agriculture.