文献类型：期刊文献

英文题名：QSAR study of mosquito repellents from terpenoid with a six-member-ring

作者：Wang, Zongde[2] Song, Jie[1] Chen, Jinzhu[2] Song, Zhanqian[3] Shang, Shibin[3] Jiang, Zhikuan[4] Han, Zhaojiu[4]

第一作者：Wang, Zongde

通信作者：Song, J[1]

机构：[1]Univ Michigan, Dept Chem & Biochem, Flint, MI 48502 USA;[2]Jiangxi Agr Univ, Coll Forestry, Nanchang 330045, Peoples R China;[3]Chinese Acad Forestry, Inst Chem Ind Forest Prod, Nanjing 210042, Peoples R China;[4]Mil Med Inst Nanjing Command, Nanjing 210002, Peoples R China

年份：2008

卷号：18

期号：9

起止页码：2854-2859

外文期刊名：BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

收录：;Scopus(收录号：2-s2.0-43049174953);WOS:【SCI-EXPANDED(收录号:WOS:000255444300018)】；

基金：Z.W., J.C., Z.S., and S.S. gratefully thank the Ministry of Science & Technology of China (No. 2006BAD06B10) for financial support. Z.W., J.C., Z.S., Z.J., and Z.H. acknowledge the National Natural Science Foundation of China (No. 30360085) and Z.W., J.C., Z.J., and Z.H. wish to thank the Fok Ying-Tong Education Foundation (No. 101031). J.S. thanks University of Michigan-Flint (RCAC award) for support.

语种：英文

外文关键词：QSAR; mosquito repellents; terpenoid; multilinear regression

摘要：A new class of low-toxicity mosquito repellents is synthesized from alpha- and beta-pinene in terpenoid compounds and preliminary biological tests show promising mosquito repellency. Statistical modeling is built using Codessa in order to reveal the quantitative relationship between the structure and the biological activity and to provide the guidance for further synthetic work. (c) 2008 Elsevier Ltd. All rights reserved.