文献类型：期刊文献

中文题名：珙桐科植物喜树灭螺机理研究

英文题名：The mechanism research of Camptotheca acuminata Decne in Nysseacea to Oncomelania hupensis

作者：尹蔚琳[1] 王万贤[1] 吴明煜[1] 唐万鹏[2] 孙启祥[3] 胡兴宜[2] 雷森林[4]

第一作者：尹蔚琳

机构：[1]湖北大学生命科学院;[2]湖北省林业科学研究院资源环境研究所;[3]中国林业科学研究院林业研究所;[4]武汉大学医学部

年份：2009

卷号：31

期号：2

起止页码：184-188

中文期刊名：湖北大学学报：自然科学版

收录：CSTPCD;;北大核心:【北大核心2008】；

基金：国家自然科学基金(30471506;30570322;39670654;30671818);"十一五"林业科技支撑项目(编号2006BAD03A15)资助

语种：中文

中文关键词：喜树碱;钉螺;毒杀作用;电镜扫描;电镜透射

外文关键词：camptothecin Oncomelania hupensis soaking liquids poisonous effect electron scanning; electron tranmission

分类号：R948.12;R122.12

摘要：在用喜树碱作用于钉螺实验中,喜树碱具有明显的灭螺效果,将喜树碱配成50、100、200、400、800mg/L,5个浓度处理4 d,200、400、800 mg/L在第4 d均达到80%以上的灭螺效果.经喜树碱提取液半致死浓度处理的钉螺,其碱性磷酸酶和谷丙转氨酶的活性均升高后下降.且钉螺头部肿胀,肌肉溃损,细胞核形态异常,微绒毛散乱,组织水肿.
In the experiment of using camptothecin to kill Oncomelania hupensis, the result showed camptothecin was effective in killing Oncomelania hupensis. Preparing camptothecin in five different concentrations for 4 days, and these concentrations were 50, 100, 200, 400 and 800 mg/L, respectively. Among these concentrations, the 200,400 and 800 mg/L could reach up to 80% in the effectiveness of killing Oncomelania hupensis on the fourth day. For those Oncomelania hupensis treated by solution LC50, the activity of their AKP and GPT showed a decrease after initial rise. In addition, the head of oncomelania swelled, its muscle festered, its nucleus were deformed, the microvillus were messy, and there occured an edema in its tissue.