文献类型：期刊文献

英文题名：NONCODEV6: an updated database dedicated to long non-coding RNA annotation in both animals and plants

作者：Zhao, Lianhe[1,2] Wang, Jiajia[3,4] Li, Yanyan[3,4] Song, Tingrui[3] Wu, Yang[1] Fang, Shuangsang[5] Bu, Dechao[1] Li, Hui[1] Sun, Liang[1] Pei, Dong[6] Zheng, Yu[3,4] Huang, Jianqin[7] Xu, Mingqing[8] Chen, Runsheng[3,9,10] Zhao, Yi[1] He, Shunmin[3,4,10]

第一作者：Zhao, Lianhe

通信作者：Zhao, Y[1];Chen, RS[2];He, SM[2];He, SM[3];Chen, RS[4];Chen, RS[5];He, SM[5]

机构：[1]Chinese Acad Sci, Adv Comp Res Ctr, Inst Comp Technol, Key Lab Intelligent Informat Proc, Beijing 100190, Peoples R China;[2]Univ Chinese Acad Sci, Beijing 100049, Peoples R China;[3]Chinese Acad Sci, Ctr Big Data Res Hlth, Inst Biophys, Key Lab RNA Biol, Beijing 100101, Peoples R China;[4]Univ Chinese Acad Sci, Coll Life Sci, Beijing 100049, Peoples R China;[5]Beijing Univ Chinese Med, Beijing 100029, Peoples R China;[6]Chinese Acad Forestry, Res Inst Forestry, State Key Lab Tree Genet & Breeding, Beijing 100091, Peoples R China;[7]Zhejiang A&F Univ, Nurturing Stn, State Key Lab Subtrop Silviculture, Hangzhou 311300, Peoples R China;[8]Shanghai Jiao Tong Univ, Bio X Inst, Key Lab Genet Dev & Neuropsychiat Disorders, Minist Educ, Shanghai 518102, Peoples R China;[9]Guangdong Geneway Decoding Biotech Co Ltd, Foshan 528316, Peoples R China;[10]Chinese Acad Sci, Natl Genom Data Ctr, Beijing 100101, Peoples R China

年份：2021

卷号：49

期号：D1

起止页码：D165-D171

外文期刊名：NUCLEIC ACIDS RESEARCH

收录：;Scopus(收录号：2-s2.0-85099427793);WOS:【SCI-EXPANDED(收录号:WOS:000608437800023)】；

基金：National Key R&D Program of China [2018YFD1000604, 2016YFC0901702, 2019YFC1709801, 2018YFC1313000, 2018YFC1313001]; National Natural Science Foundation of China [31672126, 91940306, 31871294, 91740113, 32070670, 31871294]; Strategic Priority Research Program of the Chinese Academy of Sciences [XDA12030100 and XDB38040300]; Natural Science Foundation for Young Scholars of China [31701141]; Innovation Project for Institute of Computing Technology, CAS [20186060]; China Postdoctoral Science Foundation [2019M660033]; China Postdoctoral Innovative Talent Foundation [BX20200068]; 13th Five-year Informatization Plan of Chinese Academy of Sciences [XXH13505-05-02]; Science and Technology Service Program of the Chinese Academy of Sciences [KFJ-STS-ZDTP-060]. Funding for open access charge: National Key Research and Development Program [2016YFC0901702].

语种：英文

摘要：NONCODE (http://www.noncode.org/) is a comprehensive database of collection and annotation of noncoding RNAs, especially long non-coding RNAs (lncRNAs) in animals. NONCODEV6 is dedicated to providing the full scope of lncRNAs across plants and animals. The number of lncRNAs in NONCODEV6 has increased from 548 640 to 644 510 since the last update in 2017. The number of human lncRNAs has increased from 172 216 to 173 112. The number of mouse lncRNAs increased from 131 697 to 131 974. The number of plant lncRNAs is 94 697. The relationship between lncRNAs in human and cancer were updated with transcriptome sequencing profiles. Three important new features were also introduced in NONCODEV6: (i) updated human lncRNA-disease relationships, especially cancer; (ii) lncRNA annotations with tissue expression profiles and predicted function in five common plants; iii) lncRNAs conservation annotation at transcript level for 23 plant species.