文献类型：期刊文献

中文题名：肉桂和同源根皮不同极性部位的成分分析及其抑菌效果

英文题名：Component and Antibacterial Activity of Different Polar Parts of Cinnamon and Homologous Root Bark

作者：张笮晦[1,2,3] 钱信怡[2] 黄广智[2] 毕良武[4]

第一作者：张笮晦

机构：[1]广西中医药大学药学院,广西南宁530200;[2]广西庚源香料有限责任公司,广西东兴538100;[3]广西中药药效研究重点实验室,广西南宁530200;[4]中国林业科学研究院林产化学工业研究所,生物质化学利用国家工程实验室,国家林业和草原局林产化学工程重点实验室,江苏省生物质能源与材料重点实验室,江苏南京210042

年份：2019

卷号：39

期号：3

起止页码：115-122

中文期刊名：林产化学与工业

外文期刊名：Chemistry and Industry of Forest Products

收录：CSTPCD;;Scopus;北大核心:【北大核心2017】；CSCD:【CSCD2019_2020】；

基金：国家重点研发计划资助项目(2018YFD0600405);广西重点研发计划资助项目(2017AB35155);广西中药药效研究重点实验室项目(16-380-29)

语种：中文

中文关键词：肉桂;根皮;黄酮类;多糖;抑菌活性

外文关键词：cinnamon;root bark;flavonoids;polysaccharide;antibacterial activity

分类号：TQ35;R284

摘要：以肉桂及其同源根皮为原料,采用80%乙醇分别对两者进行回流提取,经系统溶剂法萃取得到两者的石油醚部位、乙酸乙酯部位、正丁醇部位和水部位,并采用滤纸片法研究各极性部位对常见的3种致病菌(金黄色葡萄球菌、大肠杆菌、绿脓杆菌)的抑菌活性。研究结果表明:相同质量的肉桂和根皮提取得到的各极性部位的质量、成分种类及含量均有所差异,其中石油醚部位所含成分大致相同,但主要成分反式肉桂醛、邻甲氧基肉桂醛含量差异较大;两者乙酸乙酯部位、正丁醇部位和水部位分别含有黄酮类,皂苷类和多糖类成分;此外根皮乙酸乙酯部位还含有邻甲氧基肉桂醛、乙酸肉桂酯,根皮水部位含有D-半乳糖。肉桂石油醚部位、根皮石油醚部位、根皮乙酸乙酯部位对3种菌均有一定的抑制作用,当这3个部位的质量浓度均为500 g/L时,对金黄色葡萄球菌、大肠杆菌、绿脓杆菌的抑菌圈直径分别大于(17.62±0.22)、(25.21±2.09)和(12.82±0.30)mm,肉桂乙酸乙酯部位抑菌作用较弱,肉桂和根皮正丁醇部位和水部位对3种供试菌种均无抑制作用。
The petroleum ether part,ethyl acetate part,n-butanol part and water part of cinnamon and root bark were obtained by reflux extraction with 80%ethanol and systematic solvent method,using cinnamon and its homologous root bark as raw materials.Their antibacterial activities against three common pathogens(Staphylococcus aureus,Escherichia coli,Pseudomonas aeruginosa)were evaluated by the filter paper method.The results indicated that the qualities,the types and contents of components of each polar parts extracted from cinnamon and root bark of the same quality were different.The contents of the main components of the two petroleum ether parts were similar,but the contents of trans-cinnamaldehyde and o-methoxycinnamaldehyde,were quite different.Flavonoids,saponins and polysaccharide were found respectively in the two ethyl acetate parts,n-butanol parts and water parts.Moreover,o-methoxy cinnamaldehyde and cinnamyl acetate were found in ethyl acetate part,D-galactose was found in water part of root bark.The petroleum ether part of cinnamon,petroleum ether part and ethyl acetate part of root bark had a certain degree of antibacterial activity against E.coli,S.aureus and P.aeruginosa.When the mass concentrations of these three parts were 500 g/L,the diameters of bacteriostasis circles for S.aureus,E.coli and P.aeruginosa were larger than(17.62±0.22),(25.21±2.09)and(12.82±0.30)mm,respectively.Ethyl acetate part of cinnamon had weaker antibacterial activity,n-butanol part and water part of both cinnamon and root bark had no antibacterial activity.