文献类型：期刊文献

中文题名：新型去氢枞基1,3,4-噁二唑的合成与表征

英文题名：Synthesis and characterization of novel dehydroabietyl-1,3,4-oxadiazoles

作者：韩春蕊[1] 宋湛谦[1] 商士斌[1] 高宏[1]

第一作者：韩春蕊

机构：[1]中国林业科学研究院林产化学工业研究所

年份：2007

卷号：27

期号：8

起止页码：42-44

中文期刊名：现代化工

外文期刊名：Modern Chemical Industry

收录：CSTPCD;;Scopus;北大核心:【北大核心2004】；CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：去氢枞基;酰肼;噁二唑;芳基;合成

外文关键词：dehydroabietyl; hydrazine; oxadiazole; aryl; synthesis

分类号：TQ225.24

摘要：以去氢枞酸为原料,经酰化得到酰氯,酰氯与85%(质量分数)水合肼反应制备出去氢枞酰肼,去氢枞酰肼再与5种芳香酰氯反应得N,N′-二酰基肼,其再经POCl3脱水闭环反应,合成了5种新的2-去氢枞基-5-芳基-1,3,4-二唑。研究了合成反应条件;每步收率均在75%以上。
Five novel 2-dehydroabietyl-5-aryl-1, 3, 4-oxadiazoles were synthesized by cyclization of N, N＇- diacylhydrazines with POCl3. N, N＇-diacylhydrazines were obtained via reacting dehydroabietyl hydrazine, which is prepared by dehydroabietic acid with PCl3 or SOCl2 and then 85% （mass ratio） NH2NH2·H2O, with aryl chloride. The synthesis conditions were studied, and the yield of every step is more than 75 %.