文献类型：期刊文献

英文题名：A Novel Insight into Screening for Antioxidant Peptides from Hazelnut Protein: Based on the Properties of Amino Acid Residues

作者：Shi, Chenshan[1] Liu, Miaomiao[1] Zhao, Hongfei[1] Lv, Zhaolin[1] Liang, Lisong[2,3,4,5] Zhang, Bolin[1]

第一作者：Shi, Chenshan

通信作者：Zhang, BL[1];Liang, LS[2];Liang, LS[3];Liang, LS[4];Liang, LS[5]

机构：[1]Beijing Forestry Univ, Coll Biol Sci & Technol, Beijing Key Lab Forest Food Proc & Safety, Beijing 100083, Peoples R China;[2]Chinese Acad Forestry, Res Inst Forestry, State Forestry & Grassland Adm, Key Lab Tree Breeding & Cultivat, Beijing 100091, Peoples R China;[3]Chinese Acad Forestry, State Key Lab Tree Genet & Breeding, Beijing 100091, Peoples R China;[4]State Forestry & Grassland Adm, Hazelnut Engn & Tech Res Ctr, Beijing 100091, Peoples R China;[5]Natl Innovat Alliance Hazelnut Ind, Beijing 100091, Peoples R China

年份：2022

卷号：11

期号：1

外文期刊名：ANTIOXIDANTS

收录：;Scopus(收录号：2-s2.0-85122238618);WOS:【SCI-EXPANDED(收录号:WOS:000758705200001)】；

基金：This work was supported by the Fundamental Research Funds for the Central Universities (No. 2015ZCQ-SW-05).

语种：英文

外文关键词：antioxidant peptide; amino acid residues; hazelnut; BIOPEP database; DFT calculation

摘要：This study used the properties of amino acid residues to screen antioxidant peptides from hazelnut protein. It was confirmed that the type and position of amino acid residues, grand average of hydropathy, and molecular weight of a peptide could be comprehensively applied to obtain desirable antioxidants after analyzing the information of synthesized dipeptides and BIOPEP database. As a result, six peptides, FSEY, QIESW, SEGFEW, IDLGTTY, GEGFFEM, and NLNQCQRYM were identified from hazelnut protein hydrolysates with higher antioxidant capacity than reduced Glutathione (GSH) against linoleic acid oxidation. The peptides having Tyr residue at C-terminal were found to prohibit the oxidation of linoleic acid better than others. Among them, peptide FSEY inhibited the rancidity of hazelnut oil very well in an oil-in-water emulsion. Additionally, quantum chemical parameters proved Tyr-residue to act as the active site of FSEY are responsible for its antioxidation. This is the first presentation of a novel approach to excavating desired antioxidant peptides against lipid oxidation from hazelnut protein via the properties of amino acid residues.