文献类型：期刊文献

中文题名：中药石斛黄酮活性成分研究进展

英文题名：Research Progress on Active Ingredients of Flavonoids in Traditional Chinese Medicine Dendrobium

作者：曾艺芸[1] 聂雪婷[1] 李振坚[1] 张萌[1] 杨业波[2] 王伟[1] 孙振元[1]

第一作者：曾艺芸

机构：[1]中国林业科学研究院林业研究所,国家林业局林木培育重点实验室,北京100091;[2]中国绿色碳汇基金会,北京100714

年份：2021

卷号：27

期号：6

起止页码：197-206

中文期刊名：中国实验方剂学杂志

外文期刊名：Chinese Journal of Experimental Traditional Medical Formulae

收录：CSTPCD;;北大核心:【北大核心2020】；CSCD:【CSCD2021_2022】；

基金：中央级公益性科研院所基本科研业务费专项(CAFYBB2017MB001);国家林业局948项目(2015-4-10)。

语种：中文

中文关键词：兰科;石斛;黄酮;糖苷;黄烷酮;花色素

外文关键词：Orchidaceae;Dendrobium;flavonoid;glycoside;flavonol;anthocyanin

分类号：R284.2;R289

摘要：石斛是益胃生津,滋阴补虚的中药,有提高免疫力、抗氧化等功效,含有丰富的黄酮活性成分,具有较高保健价值。从多个石斛中共分离得到89个黄酮活性成分,主要分为黄酮类、黄烷酮类、黄酮醇类3种。其中黄酮类成分40个,苷元类型主要为芹菜素和圣金草素;黄烷酮类成分20个;黄酮醇类成分15个,苷元类型主要为山柰酚和槲皮素。铁皮石斛及个别种还含有二氢黄酮醇类、花色素类、查尔酮类等黄酮类型成分。含有黄酮活性成分的石斛属植物有34个种,铁皮石斛含38个黄酮成分,霍山石斛含28个黄酮成分,紫皮石斛(齿瓣石斛)含19个黄酮成分,大苞鞘石斛含12个黄酮成分,球花石斛含有5个黄酮成分,叠鞘石斛和棒节石斛各含有4个黄酮活性成分。霍山石斛中含有大量以芹菜素为苷元的黄酮活性成分,紫皮石斛中含有多数以山柰酚或槲皮素为苷元的黄酮活性成分。常见的黄酮活性成分有柚皮素、槲皮素、芦丁等,具有抗氧化、降血糖、可改善血液循环、降低胆固醇,对心血管系统具有保护作用等药理活性作用。笔者拟对中药石斛黄酮活性成分的数量、类型、生理功能等研究现状进行了综述,以期推动药用石斛业内对石斛黄酮的关注,有助于挖掘石斛属植物在药效、食品领域的价值。
Dendrobium(Orchidaceae)is traditional Chinese medicine with a high healthcare value,which can nourish Yin and tonify deficiency.Eighty-nine flavonoids were isolated from Dendrobium,mainly including flavones,flavanoes and flavonols.Among them,there were 40 flavonoids,the main aglycones were apigenin and chrysoeriol;20 flavanones;and 15 flavonols,and the main aglycones were kaempferol and quercetin.D.officinale and several other species also have flavanonols,anthocyanidins,chalcone and isoflavones.There were 34 species of Dendrobium containing flavonoids,including 38 flavonoids in D.officinale,28 flavonoids in D.huoshanense,19 flavonoids in D.devonianum,12 flavonoids in D.wardianum,5 flavonoids in D.thyrsiflorum,4 flavonoids in D.denneanum and D.findlayanum.Common flavonoids included naringenin,quercetin,rutin,which had pharmacological effects of resisting oxidation,lowering blood sugar,improving blood circulation,lowing cholesterol,and protecting the cardiovascular system.The existing studies of Dendrobium-related species,flavonoids and their physiological functions were reviewed in the expectation to promote the attention of the industry to Dendrobium flavonoids and explore values of Dendrobium plants in efficacy and food fields.