文献类型：期刊文献

中文题名：保幼激素和蜕皮激素调控昆虫变态发育机制的进展

英文题名：Advances in Molecular Mechanism of Juvenile Hormone and Molting Hormone-mediated Metamorphosis

作者：柳鹏飞[1] 王伟伟[1] 凌晓霏[1] 陆沁[1] 张金稳[1] 汪伟[1] 陈航[1]

第一作者：柳鹏飞

机构：[1]中国林业科学研究院资源昆虫研究所国家林业和草原局资源昆虫培育与利用重点实验室,昆明650224

年份：2021

卷号：40

期号：5

起止页码：2054-2062

中文期刊名：基因组学与应用生物学

外文期刊名：Genomics and Applied Biology

收录：CSTPCD;;北大核心:【北大核心2020】；CSCD:【CSCD2021_2022】；

基金：国家自然科学基金面上项目(31772542);云南省昆虫分子生态与进化创新团队培育项目(202005AE160011)共同资助

语种：中文

中文关键词：变态发育;保幼激素;蜕皮激素;交互作用

外文关键词：Metamorphosis;Juvenile hormone;20-hydroxyecdysone;Interaction

分类号：Q965

摘要：变态发育是昆虫适应生态环境和气候变化的主要生存策略之一。保幼激素(juvenile hormone,JH)和蜕皮激素(20-hydroxyecdysone,20E)的相互作用主要调控昆虫组织凋亡和重建、蜕皮等变态生理活动,近年来保幼激素和蜕皮激素调控昆虫变态发育的分子机制取得了较大的进展。本研究总结了JH和20E的合成代谢、信号传递通路及基因调控的分子途径;阐述了JH-Met和20E-EcR-USP偶联及其信号传递过程、JH/Met上调抗变态因子Kr-h1的表达抑制昆虫变态发育的调控机制及其信号通路间的内在联系;对未来潜在的研究方向进行了展望,以期为资源昆虫的利用和农林业害虫的防治提供参考。
Metamorphosis is one of the main survival strategies for insects to adapt to ecological environment and climate change.The interaction of juvenile hormone(JH)and molting hormone(20-hydroxyecdysone,20 E)mainly regulate metamorphosis physiological behaviors,including cell apoptosis,tissue reconstruction and ecdysis.Recently,the great advances have been made in the molecular mechanisms of JH and 20 E regulating metamorphosis of insects.The paper summarized the process of JH and 20 E synthesis metabolism,signal transduction pathway,regulating genes molecular pathway,meanwhile,expounded the combine process and signal pathway of JH-Met and20 E-EcR-USP complex,the mechanism that the JH/Met up-regulated Kr-h1 to inhibit insect metamorphosis,and the inner connection between JH and 20 E.We predicted the future potential research directions of insect metamorphosis,in order to provide inferences for the utilization of resource insects and the precaution of agroforestry pest.