文献类型：期刊文献

英文题名：Transcription Factors Involved in Plant Stress and Growth and Development: NAC

作者：Zheng, Chenjia[1,2] Yang, Qin[2,3] Wang, Xin[1] Chen, Yu[4] He, Ruoyu[2,3] Li, Xinmeng[2,3] Pan, Huanhuan[2,3] Zhuo, Renying[2] Qu, Tongbao[5] Qiu, Wenmin[2]

第一作者：Zheng, Chenjia

通信作者：Qiu, WM[1];Qu, TB[2]

机构：[1]Jilin Agr Univ, Coll Hort, Changchun 130118, Peoples R China;[2]Chinese Acad Forestry, Res Inst Subtrop Forestry, State Key Lab Tree Genet & Breeding, Key Lab Tree Breeding Zhejiang Prov, Hangzhou 311400, Peoples R China;[3]China Three Gorges Univ, Biotechnol Res Ctr, Key Lab Three Gorges Reg Plant Genet & Germplasm E, Yichang 443002, Peoples R China;[4]Agr Technol Extens Ctr Dongtai, Yancheng 224200, Peoples R China;[5]Jilin Agr Univ, Coll Forestry & Grassland Sci, Changchun 130118, Peoples R China

年份：2025

卷号：15

期号：4

外文期刊名：AGRONOMY-BASEL

收录：;Scopus(收录号：2-s2.0-105003702432);WOS:【SCI-EXPANDED(收录号:WOS:001474785400001)】；

基金：This research was supported by the National Key Research and Development Program of China (2021YFD2200201).

语种：英文

外文关键词：abiotic stress; biotic stress; regulatory mechanisms

摘要：Transcription factors play a key role in plant growth and development. As the largest family of plant-specific transcription factors, the NAC family plays a central role in coordinating plant growth and development and environmental adaptation through its unique molecular design paradigm of "fixed N-terminal structural domain + variable C-terminal regulatory domain". This review systematically analyses the multidimensional regulatory mechanisms of NAC transcription factors in developmental processes such as cell wall remodelling, root system architecture, leaf senescence and fruit ripening, and reveals their molecular basis for responding to biotic/abiotic stresses through strategies such as hormone signalling integration (ABA, SA, JA, etc.), antioxidant defence activation and metabolic reprogramming. The study found that NAC proteins precisely control plant growth through multiple regulatory mechanisms and have evolved to form both conservative and diverse functional modules, which are of great value for crop improvement. However, research still faces three major challenges: the NAC regulatory network in different crops is still unclear, the coordinated response to multiple stresses has not been solved, and the ecological risks of gene editing have not been assessed. To this end, this paper proposes to build an 'NAC regulatory map database' and use synthetic biology and artificial intelligence technology to design smarter, stress-tolerant and high-yielding crops, overcoming the limitations of traditional research.