文献类型：期刊文献

英文题名：Construction of antimicrobial and biocompatible cotton textile based on quaternary ammonium salt from rosin acid

作者：Li, Zhaoshuang[1] Cheng, Jiang[1] Yang, Xinxin[1] Liu, He[1] Xu, Xu[2] Ma, Lina[3] Shang, Shibin[1] Song, Zhanqian[1]

第一作者：Li, Zhaoshuang

通信作者：Liu, H[1];Song, ZQ[1];Ma, L[2]|[a0005c3716bb5fed5ea85]宋湛谦;

机构：[1]Chinese Acad Forestry, Coinnovat Ctr Efficient Proc & Utilizat Forest Re, Natl Engn Lab Biomass Chem Utilizat,Inst Chem Ind, Key Lab Chem Engn Forest Prod,Natl Forestry & Gra, Nanjing 210042, Jiangsu, Peoples R China;[2]Nanjing Forestry Univ, Coll Chem Engn, Coinnovat Ctr Efficient Proc & Utilizat Forest Re, Jiangsu Prov Key Lab Chem & Utilizat Agroforest B, Nanjing 210037, Jiangsu, Peoples R China;[3]Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China

年份：2020

卷号：150

起止页码：1-8

外文期刊名：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

收录：;EI(收录号：20240815601851);Scopus(收录号：2-s2.0-85079165430);WOS:【SCI-EXPANDED(收录号:WOS:000525869500001)】；

基金：The authors express their gratitude for financial support from the Foundation of Jiangsu Province Biomass Energy and Material Laboratory (JSBEM-S-201905) and National Natural Science Foundation of China (31570562).

语种：英文

外文关键词：Cotton textile; Quaternary ammonium salt; Rosin acid; Antimicrobial; Antibiofilm; Biocompatibility

摘要：Antimicrobial cotton textiles (CT) show great promise for wound dressings. However, modifying CTs to have antimicrobial properties requires balancing the killing of microbes while protecting normal cells. In this study, the surface of CT was modified using maleopimaric acid quaternary ammonium cations (MPA-N+) from rosin acid. The surfaces morphology and chemical composition were determined by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS), which confirmed that the MPA-N+ modified CT (CT-g-MPA-N+) was prepared. CT-g-MPA-N+ shows strong and broad spectrum antimicrobial activities against Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and Gram-positive bacteria (Staphylococcus aureus). It also exhibits prominent durability of antimicrobial capability even after soaking in PBS for 6 days, and can effectively inhibit bacterial biofilm formation. Most importantly, the excellent biocompatibility of CT-g-MPA-N+ was verified by hemocompatible and cytotoxic assays. This work is believed to be promising method to prepare antimicrobial cotton textiles by surface modification and suggest the great potential application in wound dressing. (C) 2020 Elsevier B.V. All rights reserved.