文献类型：期刊文献

英文题名：The Flavonoid Biosynthesis Network in Plants

作者：Liu, Weixin[1,2] Feng, Yi[1,2] Yu, Suhang[1,2] Fan, Zhengqi[1,2] Li, Xinlei[1,2] Li, Jiyuan[1,2] Yin, Hengfu[1,2]

第一作者：刘伟鑫

通信作者：Li, JY[1];Yin, HF[1];Li, JY[2];Yin, HF[2]

机构：[1]Chinese Acad Forestry, Res Inst Subtrop Forestry, State Key Lab Tree Genet & Breeding, Hangzhou 311400, Peoples R China;[2]Chinese Acad Forestry, Res Inst Subtrop Forestry, Key Lab Forest Genet & Breeding, Hangzhou 311400, Peoples R China

年份：2021

卷号：22

期号：23

外文期刊名：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

收录：;Scopus(收录号：2-s2.0-85119936379);WOS:【SCI-EXPANDED(收录号:WOS:000734801200001)】；

基金：FundingThis work was funded by National Key R&D Program of China (2019YFD1000), Fundamental Research Funds of CAF (CAFYBB2021QD001-1), and Zhejiang Science and Technology Major Program on Agricultural New Variety Breeding (2021C02071-2).

语种：英文

外文关键词：flavonoids; biosynthesis; molecular structure; biosynthetic enzyme; gene regulation

摘要：Flavonoids are an important class of secondary metabolites widely found in plants, contributing to plant growth and development and having prominent applications in food and medicine. The biosynthesis of flavonoids has long been the focus of intense research in plant biology. Flavonoids are derived from the phenylpropanoid metabolic pathway, and have a basic structure that comprises a C15 benzene ring structure of C6-C3-C6. Over recent decades, a considerable number of studies have been directed at elucidating the mechanisms involved in flavonoid biosynthesis in plants. In this review, we systematically summarize the flavonoid biosynthetic pathway. We further assemble an exhaustive map of flavonoid biosynthesis in plants comprising eight branches (stilbene, aurone, flavone, isoflavone, flavonol, phlobaphene, proanthocyanidin, and anthocyanin biosynthesis) and four important intermediate metabolites (chalcone, flavanone, dihydroflavonol, and leucoanthocyanidin). This review affords a comprehensive overview of the current knowledge regarding flavonoid biosynthesis, and provides the theoretical basis for further elucidating the pathways involved in the biosynthesis of flavonoids, which will aid in better understanding their functions and potential uses.