详细信息
Revitalizing Multiple Bioactivities of the Lignin-Carbohydrate Complex through a Two-Step Strategy: Unraveling the Enhancement Origin from a Structural Variation Perspective ( SCI-EXPANDED收录 EI收录) 被引量:8
文献类型:期刊文献
英文题名:Revitalizing Multiple Bioactivities of the Lignin-Carbohydrate Complex through a Two-Step Strategy: Unraveling the Enhancement Origin from a Structural Variation Perspective
作者:Su, Chen[1,2,3] Wang, Xiu[3,4] Deng, Yongjun[1] Wu, Ting[1] Jiao, Jian[1] Huang, Chen[1] Cao, Yunfeng[3] Dai, Hongqi[3] Fang, Guigan[1,2,3]
第一作者:Su, Chen
通信作者:Wu, T[1];Fang, GG[1];Fang, GG[2];Fang, GG[3]
机构:[1]Chinese Acad Forestry, Inst Chem Ind Forest Prod, Nanjing 210042, Peoples R China;[2]Key Lab Biomass Energy & Mat, Nanjing 210042, Jiangsu, Peoples R China;[3]Nanjing Forestry Univ, Coinnovat Ctr Efficient Proc & Utilizat Forest Res, Nanjing 210037, Peoples R China;[4]Peking Univ, Sch Mat Sci & Engn, Key Lab Polymer Chem & Phys, Minist Educ, Beijing 100871, Peoples R China
年份:2024
卷号:12
期号:28
起止页码:10544-10554
外文期刊名:ACS SUSTAINABLE CHEMISTRY & ENGINEERING
收录:;EI(收录号:20242716605213);Scopus(收录号:2-s2.0-85197621469);WOS:【SCI-EXPANDED(收录号:WOS:001259915300001)】;
基金:The authors acknowledge the financial support from Key Lab. of Biomass Energy and Material, Jiangsu Province (JSBEM-S-202316), the National Natural Science Foundation of China (No. 22308373), and Taishan Industry Experts Program (tscy20200213). They thank Dr. Ruibin Wang (University of South China) for revising the draft of this paper.
语种:英文
外文关键词:lignin-carbohydrate complex; bioactivities; LiCl/DMSO-NaOH separation; enzymatic hydrolysis; structure-activity relationship
摘要:Lignin-carbohydrate complex (LCC) possesses great potential in pharmaceutical and nutraceutical fields. However, the limited bioactivities and ambiguous structure-activity relationships impede its further advances in practical applications. Here, a meticulously designed sequential two-step method, i.e., LiCl/DMSO-NaOH separation combined with enzymatic hydrolysis, was used to fabricate enzymatic LCC (ELCC) with excellent bioactivities. The antioxidant and antibacterial properties of ELCC were increased by 57 and 58% compared to those of nonenzymatic LCC and showed 49 and 46% higher than that of milled wood lignin (MWL) toward the ABTS radical and E. coil. Ultimately, ELCC also exhibited a high ultraviolet (UV)-blocking rate of 96%, outperforming both LCC (84%) and MWL (87%). The superior performance was attributed to the increased bioactive groups, mainly phenolic hydroxyl (-OH), carboxyl (-COOH), and C=C bonds, which were confirmed by revelation of the structure-activity relationships. Overall, our work demonstrated an innovative approach to revitalizing the bioactivities of LCC, prospectively boosting its practical applications in various biological fields.
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