文献类型：期刊文献

英文题名：Turpentine-Derived sec-p-Menthane-1-amine Derivatives: Synthesis, Herbicidal Activity, and 3D-QSAR Study

作者：Zhang, Hongmei[1,2,3,4,5] Wang, Jing[1,2,3,4,5] Chen, Yuxiang[1,2,3,4] Xu, Shichao[1,2,3,4] Duan, Wengui[6] Jiang, Jianxin[5] Zhao, Zhendong[1,2,3,4]

第一作者：Zhang, Hongmei

通信作者：Zhao, ZD[1];Zhao, ZD[2];Zhao, ZD[3];Zhao, ZD[4];Jiang, JX[5];Duan, WG[6]

机构：[1]Chinese Acad Forestry, Natl Engn Lab Biomass Chem Utilizat, Nanjing 210042, Peoples R China;[2]Chinese Acad Forestry, Key Lab Chem Engn Forest Prod, Natl Forestry & Grassland Adm, Nanjing 210042, Peoples R China;[3]Chinese Acad Forestry, Jiangsu Coinnovat Ctr Efficient Proc & Utilizat F, Nanjing 210042, Peoples R China;[4]Chinese Acad Forestry, Inst Chem Ind Forest Prod, Nanjing 210042, Peoples R China;[5]Beijing Forestry Univ, Coll Mat Sci & Technol, Beijing 100083, Peoples R China;[6]Guangxi Univ, Sch Chem & Chem Engn, Nanning 530004, Peoples R China

年份：2022

卷号：7

期号：16

外文期刊名：CHEMISTRYSELECT

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000786614700001)】；

基金：The authors are grateful for the financial support from the National Natural Science Foundation of China (No. 31870557). The authors are grateful for the Discovery Studio software support from Multi-function Computer Center of Guangxi University.

语种：英文

外文关键词：botanical herbicide; turpentine; herbicidal activity; 3D-QSAR study

摘要：In this study, a series of turpentine-derived secondary amines (4a-4y) were synthesized and their structures were characterized by FTIR, (HNMR)-H-1, (13) CNMR, and HRMS. The post-emergence herbicidal activities against barnyard grass and rape were evaluated by the Petri dish method. The preliminary results showed that most of the amines exhibited higher herbicidal activities than that of glyphosate. Compound 4n was the most potential compound whose IC50 values against root and shoot growth of barnyard grass were 1.75 mg L-1, and 9.33 mg L-1 against shoot growth of rape was 13.12 mg L-1, which were 6.9-folds, 4.5-folds, and 13.5-folds, higher than that of glyphosate, respectively. In addition, compounds 4e, 4c, and 4n were found to be selective to monocotyledons such as Lolium perenne, Setann viridis, Digitono sanguinalis and Echinochloo crus-galli, and they were safe to wheat, sorghum, maize, and peanut at 100 mg L-1. Furthermore, a 3D-QSAR model was built by the CoMFA method to study the relationship between herbicidal activities with structures, and its coefficient were r(2) = 0.85, q(2) =0.58, indicating the 3D-QSAR model was reasonable and predictable.