文献类型：期刊文献

英文题名：Novel triphenylamine-based fluorescent probe for specific detection and bioimaging of OCl-

作者：Jiang, Yuhang[1] Zhang, Sheng[1] Wang, Bingxiang[1] Qian, Tao[4] Jin, Can[2] Wu, Shishan[3] Shen, Jian[1,3]

第一作者：Jiang, Yuhang

通信作者：Shen, J[1];Jin, C[2];Wu, SS[3]

机构：[1]Nanjing Normal Univ, Jiangsu Collaborat Innovat Ctr Biomed Funct Mat, Nanjing 210023, Jiangsu, Peoples R China;[2]Chinese Acad Forestry, Inst Chem Ind Forest Prod, Key Lab Biomass Energy & Mat Jiangsu Prov, Nanjing 210042, Jiangsu, Peoples R China;[3]Nanjing Univ, Sch Chem & Chem Engn, Nanjing 210093, Jiangsu, Peoples R China;[4]Soochow Univ, Coll Energy, Soochow Inst Energy & Mat Innovat, Suzhou 215006, Peoples R China

年份：2018

卷号：74

期号：39

起止页码：5733-5738

外文期刊名：TETRAHEDRON

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000444664000017)】；

基金：This work was supported the China Postdoctoral Fund Surface Project (2017M610335), Fundamental Research Funds of Jiangsu Key Lab. of Biomass Energy and Material (JSBEM-S-201806) and a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).

语种：英文

外文关键词：Hypochlorite; Detection limit; Triphenylamine; Fluorescence probe; Cell imaging

摘要：Hypochlorite (OCl-) plays important roles both in physiological and pathological processes, the detection of which is of great significance. Herein, a novel fluorescent probe based on the triphenylamine-type schiff base derivative (TPAD) was developed to detect OCl-. Probe TPAD exhibited specific fluorescence response toward ClO- with the fluorescence quenching rate up to 80%, and the detection limit was estimated to be 0.8 mu M. The sensing mechanism study demonstrated that TPAD reacted with ClO- via an oxidation process, which was evidenced by MS and NMR characterization. Moreover, owing to the excellent sensing properties and negligible cytotoxicity, TPAD was successfully applied in the bioimaging of OCl- in living A549 cells. (C) 2018 Elsevier Ltd. All rights reserved.