文献类型：期刊文献

英文题名：Two new steroidal sapogenins from Rohdea chinensis (synonym Tupistra chinensis) rhizomes and their antifungal activity

作者：Yao, Shu-Feng[1,2,3] Zhang, Hai-Bo[1] Cai, Zhao-Sheng[3] Gao, Hong[1] Wang, Dan[1] Shang, Shi-Bin[1,2]

第一作者：Yao, Shu-Feng

通信作者：Shang, SB[1]

机构：[1]Chinese Acad Forestry, Inst Chem Ind Forest Prod, Key Lab Biomass Energy & Mat, Key Lab Chem Engn Forest Prod,Natl Forestry & Gra, Nanjing 210042, Jiangsu, Peoples R China;[2]Nanjing Forestry Univ, Coinnovat Ctr Efficient Proc & Utilizat Forest Re, Nanjing 210037, Peoples R China;[3]Yancheng Inst Technol, Sch Chem & Chem Engn, Yancheng 224051, Peoples R China

年份：2022

卷号：24

期号：2

起止页码：153-162

外文期刊名：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

收录：;Scopus(收录号：2-s2.0-85100939276);WOS:【SCI-EXPANDED(收录号:WOS:000617981300001)】；

基金：This work was supported by the National Key Research and Development Program of China (Grant No. 2016YFD0600804).

语种：英文

外文关键词：Rohdea chinensis; steroidal sapogenins; acyloxy-compound; Rhizopus stolonifera; Penicillium digitatum

摘要：Two novel acylated steroidal sapogenins, 3 beta-acetoxy-1 alpha, 2 alpha, 4 beta, 5 alpha, 7 alpha-pentahydroxy-spirost-25(27)-en-6-one (1) and (25S)-3 alpha-acetoxy-1 alpha, 2 beta, 4 alpha, 5 alpha, 7 alpha-pentahydroxyspirostan-6-one (2), together with two known steroidal sapogenins (3 and 4), were isolated from Rohdea chinensis rhizomes. Their structures were elucidated by nuclear magnetic resonance (NMR) and mass spectrometry (MS) data. In addition, the antifungal activities of the isolated compounds against Penicillium digitatum and Rhizopus stolonifera were evaluated. Compound 2 significantly inhibited R. stolonifera growth, which was comparable to the positive control (sodium benzoate and carbendazim). Compound 4 showed the highest potency to inhibit P. digitatum growth compared to other compounds.