文献类型：期刊文献

英文题名：Biosynthesis and Its Regulatory Mechanisms of 2-(2-Phenylethyl)chromones in Agarwood

作者：Wu, Wenli[1] Jiang, Xiaoyang[1] Jiang, Luyuan[1] Wilson, Iain[2] Shao, Fenjuan[1] Qiu, Deyou[1]

第一作者：Wu, Wenli

通信作者：Shao, FJ[1]

机构：[1]Chinese Acad Forestry, Res Inst Forestry, State Key Lab Tree Genet & Breeding, Key Lab Tree Breeding & Cultivat Natl Forestry & G, Beijing 100091, Peoples R China;[2]CSIRO Agr & Food, Canberra, ACT 2601, Australia

年份：2025

卷号：14

期号：7

外文期刊名：PLANTS-BASEL

收录：;Scopus(收录号：2-s2.0-105002384548);WOS:【SCI-EXPANDED(收录号:WOS:001463619700001)】；

基金：This work was supported by the Special Funds for Central Public-Interest Scientific Institution Public Welfare Projects (grant numbers CAFYBB2024MA021).

语种：英文

外文关键词：2-(2-phenylethyl)chromones; structure and function; biosynthesis pathway; regulatory mechanisms

摘要：Agarwood, a highly prized traditional medicinal material and natural spice, holds significant economic and medicinal value. Widely utilized as a fragrant agent, it is also employed in the treatment of diverse ailments, including rheumatism, fever, asthma, bronchitis, cancer, and gastrointestinal or reproductive disorders. These functions are primarily attributed to the accumulation of 2-(2-phenylethyl)chromones (PECs), a class of bioactive compounds. In recent years, PECs have emerged as critical components in the development of agarwood-derived pharmaceuticals and commercial products, garnering substantial scientific attention. This review consolidates current advancements in the structure and function of PECs and examines and discusses the structural genes and regulatory transcription factors associated with PECs biosynthesis. By synthesizing this knowledge, this review establishes a foundation for elucidating the complete biosynthetic pathways and regulatory mechanisms governing PECs production, thereby facilitating future research and applications.