文献类型：期刊文献

英文题名：Comprehensive Mechanism of Gene Silencing and Its Role in Plant Growth and Development

作者：El-Sappah, Ahmed H.[1,2,3] Yan, Kuan[1,3] Huang, Qiulan[1,3,4] Islam, Md. Monirul[5] Li, Quanzi[6,7] Wang, Yu[1,3] Khan, Muhammad Sarwar[8] Zhao, Xianming[1,3] Mir, Reyazul Rouf[9] Li, Jia[1,3] El-Tarabily, Khaled A.[10,11] Abbas, Manzar[1,3]

第一作者：El-Sappah, Ahmed H.

通信作者：Li, J[1];Abbas, M[1];El-Tarabily, KA[2];El-Tarabily, KA[3]

机构：[1]Yibin Univ, Sch Agr Forestry & Food Engn, Yibin, Peoples R China;[2]Zagazig Univ, Dept Genet, Fac Agr, Zagazig, Egypt;[3]Key Lab Sichuan Prov Refining Sichuan Tea, Yibin, Peoples R China;[4]Yibin Univ, Coll Tea Sci, Yibin, Peoples R China;[5]Northwest A&F Univ, Coll Hort, Xianyang, Peoples R China;[6]Chinese Acad Forestry, State Key Lab Tree Genet & Breeding, Beijing, Peoples R China;[7]Chinese Acad Forestry, Res Inst Forestry, Beijing, Peoples R China;[8]Univ Agr Faisalabad, Ctr Agr Biochem & Biotechnol, Faisalabad, Pakistan;[9]Sher e Kashmir Univ Agr Sci & Technol SKUAST K, Fac Agr FoA, Div Genet & Plant Breeding, Sopore, India;[10]United Arab Emirates Univ, Dept Biol, Coll Sci, Al Ain, U Arab Emirates;[11]Murdoch Univ, Harry Butler Inst, Murdoch, WA, Australia

年份：2021

卷号：12

外文期刊名：FRONTIERS IN PLANT SCIENCE

收录：;Scopus(收录号：2-s2.0-85115865255);WOS:【SCI-EXPANDED(收录号:WOS:000703790100001)】；

基金：This study was supported by the Sichuan Provincial Department of Science and Technology Project (Grant No. 18ZDYF0293), the Key Laboratory of Sichuan Province for Refining Sichuan Tea, and the Sichuan Province Tea Industry Group Co., Ltd.

语种：英文

外文关键词：transcriptional gene silencing; post-transcriptional gene silencing; genomics imprinting; paramutation; RNAi; CRISPR; Cas9

摘要：Gene silencing is a negative feedback mechanism that regulates gene expression to define cell fate and also regulates metabolism and gene expression throughout the life of an organism. In plants, gene silencing occurs via transcriptional gene silencing (TGS) and post-transcriptional gene silencing (PTGS). TGS obscures transcription via the methylation of 5 ' untranslated region (5 ' UTR), whereas PTGS causes the methylation of a coding region to result in transcript degradation. In this review, we summarized the history and molecular mechanisms of gene silencing and underlined its specific role in plant growth and crop production.