文献类型：期刊文献

英文题名：Sustainable production 3-bromobutyrates and 3-hydroxybutyrates from bioderived poly-3-hydroxybutyrate

作者：Kang, Shimin[1] Tang, Peifeng[2,3] Liang, Jianhao[1] Fu, Jinxia[4] Chen, Jintao[1] Zheng, Xiting[1] Wang, Juntao[1] Ye, Jun[5] Xu, Yongjun[1]

第一作者：Kang, Shimin

通信作者：Kang, SM[1];Xu, YJ[1];Ye, J[2]

机构：[1]Dongguan Univ Technol, Guangdong Prov Key Lab Distributed Energy Syst, Dongguan 523808, Guangdong, Peoples R China;[2]Beibu Gulf Univ, Coll Marine Sci, Guangxi Key Lab Beibu Gulf Marine Biodivers Conser, Qinzhou 535011, Peoples R China;[3]Suzhou NewBerry Technol Co Ltd, Shanghai, Peoples R China;[4]Univ Hawaii Manoa, Hawaii Nat Energy Inst, Honolulu, HI 96822 USA;[5]Chinese Acad Forestry, Inst Chem Ind Forest Prod, Beijing, Peoples R China

年份：2023

卷号：36

外文期刊名：SUSTAINABLE CHEMISTRY AND PHARMACY

收录：;EI(收录号：20230229425);Scopus(收录号：2-s2.0-85173124056);WOS:【SCI-EXPANDED(收录号:WOS:001165161400001)】；

基金：This work was supported by the funding of Guangdong Provincial Key Laboratory of Distributed Energy Systems (2020B1212060075), Guangdong Basic and Applied Basic Research Foundation (2022A1515010578), the College Students'Climbing Plan of Guangdong Province (pdjh2022a0508; pdjh2023a0507), the 2023 Songshan Lake Science and Technology Commissioner (Shimin Kang as project leader), and Guangdong Provincial University Innovation Team Project (2023KCXTD038).

语种：英文

外文关键词：Poly-3-hydroxybutyrate; 3-Hydroxybutyric acid; 3-Bromobutyric acid; 3-Bromobutyrates; 3-Hydroxybutyrates

摘要：The efficient and effective degradation of bio-polymer poly-3-hydroxybutyrate (PHB) has emerged as a prominent research focus. In this investigation, we explored the valorization of PHB to 3-bromobutyrates and 3-hydroxybutyrates employing hydrogen bromide (HBr) as a catalyst at relatively mild temperatures (70-110 C-degrees). Comprehensive investigations were conducted on re-action solvent systems (HBr solution and HBr-HAc (acetic acid) solution) along with process para-meters. The impact of these variables is systematically assessed using JMP13 software. In the HBr solution, both 3-hydroxybutyric acid (3HA) and 3-bromobutyric acid (3BA) are identified as the primary products. Remarkably, a high 3HA yield of up to 96.3 mol% is achieved at 70 C-degrees, while the 3BA yield remains below 52 mol% within the tested temperature range. Conversely, the HBr-HAc solution yields a favorable 3BA (>99 mol%). Furthermore, we demonstrate a strategy for synthesizing various 3-bromobutyrates through a tandem degradation-esterification process. The utilization of HBr catalysis presents compelling advantages, including a straightforward process conducted under mild conditions, facilitating the complete degradation of PHB into the desired target products with notably high molar yields.