文献类型：期刊文献

英文题名：Red Fluorescent Molecule with Aggregation-Induced Emission Based on Dehydroabietic Acid Diarylamine for Bioimaging

作者：Dou, Liwei[1,2] Xu, Lijun[1,2] Gao, Hong[1] Song, Jie[3] Shang, Shibin[1] Song, Zhanqian[1]

第一作者：Dou, Liwei

通信作者：Gao, H[1]

机构：[1]Chinese Acad Forestry, Inst Chem Ind Forest Prod, Natl Forestry & Grassland Adm,Natl Engn Res Ctr Lo, Key Lab Biomass Energy & Mat Jiangsu Prov,Key Lab, Nanjing 210042, Peoples R China;[2]Nanjing Forestry Univ, Coll Chem Engn, Jiangsu Coinnovat Ctr Efficient Proc & Utilizat Fo, Nanjing 210037, Peoples R China;[3]Univ Michigan Flint, Dept Chem & Biochem, Flint, MI 48502 USA

年份：2024

外文期刊名：JOURNAL OF FLUORESCENCE

收录：;EI(收录号：20241715974826);Scopus(收录号：2-s2.0-85191076076);WOS:【SCI-EXPANDED(收录号:WOS:001207146500002)】；

基金：The authors thank the National Natural Science Foundation of China (No. 32171729) for financial support.

语种：英文

外文关键词：Rosin; Dehydroabietic acid diarylamine; Red aggregation-induced emission; Bioimaging in vitro and in vivo

摘要：In this paper, molecules with AIE red light properties were designed by coupling dehydroabietic acid diarylamine and 2,3-diphenylfumaronitrile, which were designated 2DTPA-CN and 2TPA-CN. The emission wavelengths were 683 nm and 701 nm, respectively. The 2DTPA-CN and 2TPA-CN showed typical AIE characteristics with large Stokes shifts of 7.4 x 104 cm-1 and 6.7 x 104 cm-1, respectively. The obvious solvatochromism and electron cloud distributions of HOMO/LUMO in the ground and excited states both reveal the intramolecular charge transfer (ICT) effect. The 2DTPA-CN, boasting exceptional biocompatibility, was successfully prepared into nanoparticles (NPs), which were applied to tumor cell imaging, showing good bioimaging effects both in vitro imaging in live cells and in vivo imaging in live mice. The results demonstrated that it possesses significant potential as an effective bioimaging reagent for the detection of tumor cells. Furthermore, the incorporation of 2,3-diphenylfumaronitrile moieties to dehydroabietic acid diarylamine emerged as a proficient approach to broaden the emission wavelengths of rosin-based fluorescent materials.