详细信息
蜡酯合成途径及关键酶的研究进展 被引量:12
Research Progress on Wax Ester Biosynthetic Pathway and the Related Key Enzymes
文献类型:期刊文献
中文题名:蜡酯合成途径及关键酶的研究进展
英文题名:Research Progress on Wax Ester Biosynthetic Pathway and the Related Key Enzymes
作者:杨璞[1] 徐冬丽[1] 陈晓鸣[1] 刘魏魏[1] 巩中军[2] 胡艳红[1]
第一作者:杨璞
机构:[1]中国林业科学研究院资源昆虫研究所,国家林业局资源昆虫培育与利用重点实验室;[2]河南省农业科学院植物保护研究所,河南省农作物病虫害防治重点实验室
年份:2012
卷号:34
期号:7
起止页码:695-703
中文期刊名:中国细胞生物学学报
外文期刊名:Chinese Journal of Cell Biology
收录:CSTPCD;;北大核心:【北大核心2011】;CSCD:【CSCD2011_2012】;
基金:国家自然科学基金青年基金(No.31000983);云南省自然科学基金(No.2010ZC235);资源昆虫研究所基本科研业务费专项(No.riri-caf200904M-3;No.riricaf2011006M)资助项目~~
语种:中文
中文关键词:蜡酯;合成途径;FAR;WS
外文关键词:wax ester; biosynthetic pathway; FAR; WS
分类号:TQ464.1
摘要:蜡酯对于生物的生命活动具有重要意义,研究表明植物和动物的蜡酯合成存在保守途径,即脂酰辅酶A(fatty acyl-CoA)在脂酰辅酶A还原酶(fatty acyl-CoA reductase,FAR)的作用下还原成脂肪醇,脂肪醇和脂酰辅酶A在蜡酯合酶(wax synthase,WS)的作用下生成酯,FAR和WS是该途径的关键酶,这两个酶的结构和功能在不同物种之间表现出很大差异,目前对于这两个酶缺乏系统的归纳分析。该文综述了蜡酯合成途径及FAR和WS的序列特征、生化特性及参与的生理功能,分析了这两种酶相关研究存在的问题,旨在为昆虫的蜡酯合成研究提供参考。
Wax esters play an important role in life activities of organisms. It has been shown that the wax ester biosynthetic pathway is highly conserved in animals and plants. In this pathway, the fatty acyl-CoA precursor is reduced to the corresponding alcohol by fatty acyl-CoA reductase (FAR) and proceeds through esterification with alcohol, which is catalyzed by the wax synthase (WS), yielding wax ester. FAR and WS are key enzymes responsible for wax biosynthesis. The structure and function of the two enzymes are different in different species. At present, there is no comprehensive analysis of the two enzymes. This paper reviews the sequence characteristics, biochemical characteristics, functions, and research status of the two enzymes, which purposes to provide reference for related researches.
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