文献类型：期刊文献

中文题名：没食子酸标准样品的制备与定值研究

英文题名：Preparation and Certification of Reference Material of Gallic Acid

作者：汪咏梅[1,2,3,4,1] 吴冬梅[1,2,3,4,1] 张亮亮[1,2,3,4,1] 徐曼[1,2,3,4] 陈笳鸿[1,2,3,4]

第一作者：汪咏梅

机构：[1]中国林业科学研究院林产化学工业研究所;[2]生物质化学利用国家工程实验室;[3]国家林业局林产化学工程重点开放性实验室;[4]江苏省生物质能源与材料重点实验室

年份：2013

期号：1

起止页码：49-53

中文期刊名：生物质化学工程

外文期刊名：Biomass Chemical Engineering

基金：科技基础性工作专项(2007FY230200)

语种：中文

中文关键词：没食子酸;标准样品;定值;均匀性检验;稳定性检验

外文关键词：gallic acid ; reference material ; certification; homogeneity test ; stability test

分类号：TQ35

摘要：研究了没食子酸标准样品的制备、均匀性和稳定性检验及其定值方法。用五倍子单宁酸水解得到的没食子酸为原料,经精制得到高纯度的没食子酸标准样品。通过红外光谱、核磁共振、热重分析证实该标准样品的化学结构式。标准样品含量测定采用高效液相色谱面积归一化法,并通过了均匀性检验和稳定性检验(15个月)。经6个实验室的联合定值,没食子酸标准样品的含量值为99.96%±0.10%。
Preparation, homogeneity, stability and certification of reference material of gallic acid were studied. Highly purified reference material of gallic acid was prepared from an industrial grade product of gallic acid by recrystallization. The chemical structural formula of gallic acid was identified by IR, NMR and thermogravimetric analysis. The content of gallic acid in reference material was measured by HPLC with area normalization method. The reference material of gallic acid passed the test of homoge- neity, and it was stable within 15 months. According to certification of six laboratories, the standard value of gallic acid content was 99.96% ± 0.10%.