文献类型：期刊文献

中文题名：3,4,5-三甲氧基苯甲酸含量测定方法的研究

英文题名：Quantitative Determination of 3,4,5-Trimethoxybenzoic Acid

作者：徐曼[1] 汪咏梅[1] 张亮亮[1] 胡新宇[1]

第一作者：徐曼

机构：[1]中国林业科学研究院林产化学工业研究所生物质化学利用国家工程实验室国家林业局林产化学工程重点开放性实验室江苏省生物质能源与材料重点实验室

年份：2018

卷号：52

期号：1

起止页码：23-28

中文期刊名：生物质化学工程

外文期刊名：Biomass Chemical Engineering

收录：北大核心:【北大核心2017】；

基金：中国林科院林产化学工业研究所团队建设创新工程项目(LHSXKQ4);林业行业标准项目资助(2015-LY-060)

语种：中文

中文关键词：3,4,5-三甲氧基苯甲酸;高效液相色谱法;化学滴定法;含量测定;统计分析

外文关键词：3,4,5-trimethoxybenzoic acid ; high performance liquid chromatography ; titration method ; quantitative determination ; statistic analysis

分类号：TQ35

摘要：比较了采用高效液相色谱法和化学滴定法2种方法测定3,4,5-三甲氧基苯甲酸的含量,提出了测定操作的实验条件,并对测定结果进行统计分析,以判断和评价2种方法的准确性和实用性。经过Grubbs检验表明2种方法的测定数据均无异常值;通过偏态系数和峰态系数来检验方法的正态性分布,统计结果表明2种方法均遵从正态分布;同时进行了2种方法测定值的均数检验(t检验),结果表明二者的测定值无显著性差异。高效液相色谱法的测定值有更高的准确度和精密度,可以作为首选,在不具备色谱仪的情况下也可使用化学滴定法。
High performance liquid chromatography and titration method were studied for quantitative determination of 3,4,5- trimethoxyhenzoie acid. The testing conditions of the methods were proposed, and the measured results were analysed to estimate and evaluate the accuracy and practical applicability of two methods. The Grubbs test results showed that there was no outlier in the two groups of measuring data determined by HPLC and titration method. The data of two methods were both in compliance with normal distribution by testing the skewness and kurtosis coefficient. The t-test of both measurements was simultaneously performed, which indicated that there was no significant difference between the determination value of two methods. The results also showed HPLC method had higher accuracy and precision compared with the titration method, so the HPLC method could be the first choice and then the titration method.