文献类型：期刊文献

中文题名：分子短程蒸馏分离银杏叶聚戊烯醇的研究

英文题名：Studies on Seperation of Polyprenols from leaves of Ginkgo biloba L. by Molecular Short Distillation

作者：王成章[1,2] 王婉苓[3] 叶建中[1,2] 郑光耀[1,2] 周昊[1,2] 陈西娟[1,2]

第一作者：王成章

机构：[1]中国林业科学研究院林产化学工业研究所;[2]国家林业局林产化学工程重点开放性实验室;[3]武汉大学电子信息学院

年份：2008

卷号：28

期号：3

起止页码：23-27

中文期刊名：林产化学与工业

外文期刊名：Chemistry and Industry of Forest Products

收录：CSTPCD;;Scopus;CSCD:【CSCD_E2011_2012】；

基金：“十一五”国家科技支撑计划(2006BAD06B09);科技部成果转化项目(2007GB24320415);国家林业局推广项目(2007-80)

语种：中文

中文关键词：银杏叶;聚戊烯醇;不皂化物;分子短程蒸馏

外文关键词：leaves of Ginkgo biloba L;polyprenols;non-saponifialble matter;molecular short distillation

分类号：TQ91

摘要：以银杏叶为原料,采用皂化反应、溶剂萃取和冷冻制备聚戊烯醇不皂化物,皂化剂为5%NaOH-EtOH,石油醚软膏与皂化剂的比例为1∶5(g∶mL),首次采用分子短程蒸馏分离聚戊烯醇不皂化物,最佳工艺为:Ⅰ级分子蒸馏,工艺参数为冷凝温度2.5℃,循环水温度60℃,物料加热温度60℃,蒸馏温度160℃,进料速率180mL/h,刮膜转速200r/min,蒸馏真空度0.5～1.0Pa;Ⅱ级分子蒸馏,工艺参数为循环水温度80℃,物料加热温度60℃,蒸馏温度280℃,进料速率180mL/h,刮膜转速300r/min,蒸馏真空0.1～0.5Pa。结果表明:溶剂中聚戊烯醇为55.6%,银杏叶聚戊烯醇(GP)回收率为98.5%,馏余物中聚戊烯醇的含量由不皂化物中的46.2%提高到83.7%,而且无溶剂残留,是工业化制备高纯度聚戊烯醇理想的分离方法。
Non-saponifiable matter of polyprenols from Ginkgo biloba L. was obtained by saponification, extraction and solvent refrigeration, using 5 % NaOH-EtOH as saponifier, ratio of paste of petroleum ether to saponifier 1 ： 5 （g： mL）. Molecular short distillation was first used to purify non-saponifiable matter of polyprenols. For the I grade molecular distillation, the optimum operation parameters were ： condensation temperature 2.5 ℃, circulating-water temperature 60℃, feed temperature 60 ℃, distillation temperature 160℃,feed flow rate 180 mL/h,scraper rate 200 r/min,operation pressure 0.5-1.0 Pa. For the II grade molecular distillation, the optimum parameters were： feed temperature 60℃, circulating water temperature 80℃, distillation temperature 280℃ , feed flow rate 180 mL/h, scraper rate 300 r/min; operation pressure 0.1-0.5 Pa. The results showed that content of polyprenols in solution was raised to 55.6 % ,recovery rate of polyprenols from G. biloba L. （GP） was 98.5 % , content of polyprenols in distillate residue could be raised from 46.2 % to 83.7 % of non-saponifiable matter, and there was no solvent residue. Thus, this mehod would be an ideal separation method to prepare high-purity polyprenols industrially.