文献类型：期刊文献

中文题名：响应面试验优化紫胶树脂钠盐为壁材制备VE微胶囊工艺

英文题名：Response Surface Methodology for Optimization of Microencapsulation of Vitamin E with Sodium Shellac as Wall Material

作者：潘正东[1] 李凯[1] 徐涓[1] 周梅村[2] 张弘[1] 郑华[1]

第一作者：潘正东

通信作者：Zhang, Hong|[a00050201897da7fe7284]张弘;

机构：[1]中国林业科学研究院资源昆虫研究所;[2]昆明理工大学化学工程学院

年份：2016

卷号：37

期号：12

起止页码：19-26

中文期刊名：食品科学

外文期刊名：Food Science

收录：CSTPCD;;EI(收录号：20162802571881);Scopus;北大核心:【北大核心2014】；CSCD:【CSCD_E2015_2016】；

基金：国家高技术研究发展计划(863计划)项目(2014AA021801)

语种：中文

中文关键词：紫胶树脂钠盐;VE;微胶囊壁材;喷雾干燥

外文关键词：sodium shellac; vitamin E; microcapsule wall material; spray drying

分类号：TS202.3;TQ351.7

摘要：为探索紫胶树脂钠盐在微胶囊壁材上的应用,将VE作为芯材,采用喷雾干燥法制备VE微胶囊。以包裹率为目标,通过单因素试验和响应面优化试验设计,对制备工艺进行了优化和分析,得到最佳工艺条件为:乳化剂亲水疏水平衡值11、乳化剂用量0.833 g、芯壁比1∶2.2。在此工艺条件下,制得的VE微胶囊为表面光滑的球型颗粒,其包裹率为78.06%,载药量为31.8%。结果表明,以紫胶树脂钠盐为壁材的VE微胶囊具有良好的热稳定性和复溶性,内容物可在中性pH值或肠内环境下释出,是一种较好的新型食品微胶囊壁材。
Sodium shellac, a thermoplastic polymer, has high surfactant activity. In this study, we attempted to fabricate vitamin E microcapsule with sodium shellac as the wall material by spray drying. The optimization of process parameters for improved microencapsulation efficiency was done using one-factor-at-a-time method and response surface methodology. It turned out that the optimal conditions for preparing vitamin E microcapsule were as follows： hydrophile-lipophile balance（HLB） of emulsifier, 11; emulsifier dosage, 0.833 g; and ratio of core to wall materials, 1：2.2. Under these conditions, the microcapsules with microencapsulation efficiency of 78.06% and drug-loading efficiency of 31.8% were obtained as spherical particles with a smooth surface. The vitamin E microcapsule had high thermal stability and good solubility, and it exhibited good release performance at neutral pH or in the intestinal environment. Thus, sodium shellac potentially could be used in the food industry as a good novel microcapsule wall material.